AS Roma are poised as clear favourites with a 65% chance of victory against US Lecce when they clash in the Serie A on March 22. Despite facing a few injury woes, including key players Matias Soule, Paulo Dybala, and Wesley’s suspension, Roma's squad depth should see them perform resiliently. Their recent European campaign showcased their fighting spirit, even in defeat, hinting that they will come into this match with determination and hunger for success.